Bioactivity of Vernonia arborea Leaves from Bentian Tribe as Natural Antioxidant and Antibacterial Based on Local Knowledge

Nur Maulida Sari, Humairo Aziza, Farida Aryani, Murdianto Murdianto

Abstract


The utilization of natural organic materials as raw materials for standardized medicine, including the use of organic materials in medicine manufacture are currently being encouraged by the Government. Based on the information from Bentian Tribe people, Vernonia arborea leaf or Kutu Bu’ut leaf has the potential to be developed as natural medicine derived from plants. This study explored the potential of V.arborea leaf for its phytochemicals screening by Harborne, Kokate and Senthilmurugan method, antioxidant analysis was evaluated by DPPH radical scavenging assay. Antibacterial analysis was examined using agar well diffusion method against Escherichia coli and Propionibacterium acnes. The results showed that the V.arborea leaf contained alkaloid on n-hexan extract and coumarin on ethyl acetate extract. Ethanol extract from V.arborea leaf contained alkaloid, flavonoid, saponin, tannin, and carbohydrate. Antioxidant activity showed that the highest inhibition by 83% at 50 ppm consentration of ethanol solvent. Antibacterial activity of E. coli and P.acnes showed that the highest inhibition zone by 12 mm and 11 mm at 400 µg/well of ethanol extract. Based on the results, the V.arborea leaf contains natural bioactivity and has potential to be further developed as a natural traditional medicine.

Keywords


Vernonia arborea; antibacterial; DPPH; traditional medicine

Full Text:

PDF

References


Ahmed, T., & Wang, C.-K. (2021). Black Garlic and Its Bioactive Compounds on Human Health Diseases: A Review. Molecules (Basel, Switzerland), 26(16). https://doi.org/10.3390/molecules26165028

Elfahmi, Woerdenbag, H. J., & Kayser, O. (2014). Jamu: Indonesian traditional herbal medicine towards rational phytopharmacological use. Journal of Herbal Medicine, 4(2), 51–73. https://doi.org/10.1016/j.hermed.2014.01.002

Heliawati, L., Lestari, S., Hasanah, U., Ajiati, D., & Kurnia, D. (2022). Phytochemical Profile of Antibacterial Agents from Red Betel Leaf (Piper crocatum Ruiz and Pav) against Bacteria in Dental Caries. Molecules (Basel, Switzerland), 27(9). https://doi.org/10.3390/molecules27092861

Indrianingsih, A. W., Tachibana, S., & Itoh, K. (2015). In Vitro Evaluation of Antioxidant and α-Glucosidase Inhibitory Assay of Several Tropical and Subtropical Plants. Procedia Environmental Sciences, 28, 639–648. https://doi.org/10.1016/j.proenv.2015.07.075

Kusuma, I. W., Murdiyanto, Arung, E. T., Syafrizal, & Kim, Y. (2014). Antimicrobial and antioxidant properties of medicinal plants used by the Bentian tribe from Indonesia. Food Science and Human Wellness, 3(3–4), 191–196. https://doi.org/10.1016/j.fshw.2014.12.004

Kusuma, I. W., Sari, N. M., Murdiyanto, & Kuspradini, H. (2016). Anticandidal activity of several plants used by Bentian tribe in East Kalimantan, Indonesia. AIP Conference Proceedings, 040002. https://doi.org/10.1063/1.4958477

Lim, T. Y., Lim, Y., & Yule, C. (2014). BIOACTIVITY OF LEAVES OF MACARANGA SPECIES. Journal of Tropical Forest Science. https://api.semanticscholar.org/CorpusID:199495488

Riaz, T., Abbasi, A., Aziz-Ur-Rehman, A., Shahzadi, T., Ajaib, M., & Khan, M. (2012a). Phytochemical screening, free radical scavenging, antioxidant activity and phenolic content of Dodonaea viscosa. Journal of the Serbian Chemical Society, 77(4), 423–435. https://doi.org/10.2298/JSC110621183R

Riaz, T., Abbasi, A., Aziz-Ur-Rehman, A., Shahzadi, T., Ajaib, M., & Khan, M. (2012b). Phytochemical screening, free radical scavenging, antioxidant activity and phenolic content of Dodonaea viscosa. Journal of the Serbian Chemical Society, 77(4), 423–435. https://doi.org/10.2298/JSC110621183R

Sari, N. M., Aryani, F., Wartomo, W., Hernandi, M. F., Rositah, E., & Prayitno, J. (2023). Phytochemical and Antioxidant Activity of Blumea balsamifera and Cordyline fruticosa Based on Ethnopharmacology Knowledge of Muara Tae Tribe, East Kalimantan. Biology, Medicine, & Natural Product Chemistry, 12(1), 273–280. https://doi.org/10.14421/biomedich.2023.121.273-280

Shimizu, K., Kondo, R., Sakai, K., Takeda, N., Nagahata, T., & Oniki, T. (2001). Novel vitamin E derivative with 4-substituted resorcinol moiety has both antioxidant and tyrosinase inhibitory properties. Lipids, 36(12), 1321–1326. https://doi.org/10.1007/s11745-001-0847-9

SILALAHI, M., SUPRIATNA, J., WALUJO, E. B., & NISYAWATI, N. (2014). Local knowledge of medicinal plants in sub-ethnic Batak Simalungun of North Sumatra, Indonesia. Biodiversitas Journal of Biological Diversity, 16(1). https://doi.org/10.13057/biodiv/d160106

Singh, B., Sahu, P. M., & Sharma, M. K. (2002). Anti-inflammatory and antimicrobial activities of triterpenoids from Strobilanthes callosus Nees. Phytomedicine, 9(4), 355–359. https://doi.org/10.1078/0944-7113-00143

Viji, G. S., Vasanthe, B., & Suresh, K. (2013). Screening and antibacterial activity analysis of some important medicinal plants. International Journal of Innovation and Applied Studies, 2(2), 146–152. http://www.ijias.issr-journals.org/abstract.php?article=IJIAS-13-005-01

Zhao, Y., Chen, S., Wang, Y., Lv, C., Wang, J., & Lu, J. (2018). Effect of drying processes on prenylflavonoid content and antioxidant activity of Epimedium koreanum Nakai. Journal of Food and Drug Analysis, 26(2), 796–806. https://doi.org/10.1016/j.jfda.2017.05.011




DOI: https://doi.org/10.14421/biomedich.2023.122.675-680

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2024 Nur Maulida Sari, Humairo Aziza, Farida Aryani, Murdianto



Biology, Medicine, & Natural Product Chemistry
ISSN 2089-6514 (paper) - ISSN 2540-9328 (online)
Published by Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity.

CC BY NC
This work is licensed under a CC BY-NC