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The Effect of Sea Urchin Gonad-Enriched Baruasa Snacks Combined with Iron Supplementation on Hemoglobin Levels in Adolescent Girls: A Non-Blinded Randomized Controlled Trial
Abstract
Adolescent girls are highly vulnerable to iron deficiency anemia, which poses long-term risks to their growth and reproductive health. This quasi-experimental study aimed to evaluate the effectiveness of a local food-based intervention, specifically baruasa snacks enriched with sea urchin gonads combined with iron supplementation, compared to iron supplementation alone, in improving hemoglobin levels among adolescent girls. A total of 70 female students aged 15–17 years were equally divided into an intervention group receiving both the enriched baruasa and iron tablets, and a control group receiving only iron tablets. Hemoglobin levels, body mass index (BMI), and mid-upper arm circumference (MUAC) were measured before and after the intervention, with data analyzed using paired and independent t-tests. The results demonstrated a highly significant improvement in the intervention group, where mean hemoglobin levels increased from 10.43 ± 1.39 g/dL to 12.34 ± 1.27 g/dL (p < 0.001, mean delta = 1.91 ± 1.57 g/dL). In contrast, the control group exhibited a marginal increase from 11.76 ± 1.71 g/dL to 11.84 ± 1.52 g/dL (p < 0.001, mean delta = 0.07 ± 0.33 g/dL). Furthermore, secondary nutritional indicators, including BMI and MUAC, showed greater improvements in the combination group. In conclusion, supplementing iron tablets with sea urchin gonad-enriched Baruasa provides a synergistic nutritional effect that significantly outperforms iron supplementation alone. This integrated approach serves as a promising, culturally acceptable, and sustainable strategy for preventing adolescent anemia.
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DOI: https://doi.org/10.14421/biomedich.2026.152.2103-2108
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